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Cyclobenzaprine Oral Route Side Effects

Cyclobenzaprine Oral Route Side Effects

As discussed above, the clinician should consider contacting the poison control center in refractory cases. A psychiatrist consult is required for deliberate poisoning of cyclobenzaprine. Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepr[7]essants. Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem.

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Cyclobenzaprine is often prescribed to people who have acute back injuries, including when people report having muscle spasms or significant tightness in their back, or when the back feels like it’s locked, she explained. No definite information exists whether weight gain is one of the Cyclobenzaprine side effects. Anecdotal evidence, however, suggests that small weight gain can occur during acute use of Flexeril.

Thus patients should be warned of these adverse drug reactions, educated on Serotonin Syndrome, and be instructed to seek immediate medical care if they notice respective signs and symptoms. When certain drugs are used with cyclobenzaprine, they may cause more severe side effects such as increased drowsiness or sedation. A person should ask their doctor whether it is safe to combine another medication with cyclobenzaprine and take care not to operate any machinery while taking it. Cyclobenzaprine belongs to a class of drugs called muscle relaxants. A class of drugs is a group of medications that work in a similar way. Flexeril is used together with rest and physical therapy to treat skeletal muscle conditions such as pain, injury, or spasms.

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If this medication upsets your stomach, take it with food or milk. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Cyclobenzaprine is usually taken taken for up to 2 or 3 weeks. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Flexeril only for the indication prescribed. Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease.

If cyclobenzaprine is beingmisused, however, the person may continue to take the medication for much longer and may increase their dose too high, which could lead to dangerous side effects and overdose. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material flexeril.live is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses.

  • During pregnancy, this medication should be used only when clearly needed.
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  • Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you.
  • Taking this drug with an MAOI or within 14 days of stopping an MAOI could increase your risk of serious side effects.
  • There is also evidence that cyclical antidepressants may decrease the seizure threshold by interfering with chloride conductance on the GABA receptor.

Furthermore, cardiovascular adverse reactions of TCAs are shared by Cyclobenzaprine and can yield fatal arrhythmias, sinus tachycardia, heart attack, and even stroke. It is of paramount importance to understand that although this article offers the most commonly encountered adverse reactions, it does not offer an exhaustive list of all possible signs and symptoms of Flexeril side effects. It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke.

What drugs interact with Flexeril?

It is available in immediate-release tablets of 5 milligrams, 7.5 milligrams, and 10 milligrams and extended-release capsules of 15 milligrams and 30 milligrams and is usually given three times daily. The extended-release formulation should be administered at the same time each day. The capsule may be swallowed whole, but its contents also may be sprinkled onto a tablespoon of applesauce for immediate consumption without chewing the granules. The patient should rinse their mouth to ensure that they have swallowed all the contents.

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Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Side Effects of Flexeril Abuse

Flexeril withdrawal symptoms can include headache, nausea, fatigue, and cravings for the drug. In case of acute cyclobenzaprine overdose, emergency medicine physicians and triage nurses should stabilize the patient. If EKG demonstrates QRS prolongation, the clinician should initiate sodium bicarbonate therapy. In severe overdose, ventricular arrhythmias and seizures may require MICU-level of care under the supervision of a critical care physician.

In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Along with its needed effects, a medicine may cause some unwanted effects.

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